Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BTHE_1237Thiamine biosynthesis protein ThiF. (237 aa)    
Predicted Functional Partners:
BTHE_1238
Thiamine biosynthesis protein ThiS.
  
 0.990
thiG
Thiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.987
BTHE_0655
Multifunctional hydroxymethylpyrimidine phosphokinase/4-amino-5-aminomethyl-2-methylpyrimidine hydrolase.
 
  
 0.799
BTHE_1931
Aminotransferase class-V.
   
 0.748
BTHE_1043
IscS/SufS Cysteine desulfurase/Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.579
pheT
PheT Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.578
BTHE_0348
Dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.
  
  
 0.518
thiE
Phosphomethylpyrimidine kinase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the thiamine-phosphate synthase family.
 
  
 0.505
BTHE_0240
Cystathionine beta-synthase.
  
 
 0.445
BTHE_0340
Transcriptional activator TenA.
 
    0.444
Your Current Organism:
Bifidobacterium thermophilum
NCBI taxonomy Id: 33905
Other names: AS 1.2235, ATCC 25525, B. thermophilum, BCRC 14669, Bifidobacterium ruminale, Bifidobacterium thermophilium, CCRC 14669, CCRC:14669, CCUG 34983, CIP 105420, DSM 20210, HAMBI 111, LMG 11573, LMG:11573
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