STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTHE_1861MFS transporter with CBS domain; Belongs to the major facilitator superfamily. (644 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.830
BTHE_1007
Glutamate synthase [NADPH] large chain.
     
 0.744
BTHE_0240
Cystathionine beta-synthase.
  
  
 0.702
BTHE_1000
GMP reductase.
  
  
 0.664
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.605
BTHE_0760
Major facilitator superfamily protein.
 
     0.522
dnaG
dnaG DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 
 0.454
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.451
BTHE_1860
Hypothetical protein.
       0.442
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 
 0.440
Your Current Organism:
Bifidobacterium thermophilum
NCBI taxonomy Id: 33905
Other names: AS 1.2235, ATCC 25525, B. thermophilum, BCRC 14669, Bifidobacterium ruminale, Bifidobacterium thermophilium, CCRC 14669, CCRC:14669, CCUG 34983, CIP 105420, DSM 20210, HAMBI 111, LMG 11573, LMG:11573
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.