STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (317 aa)    
Predicted Functional Partners:
SMC16857.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.974
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.942
SMC17678.1
Pyruvate dehydrogenase E1 component beta subunit.
   
 0.918
SMC15659.1
Fructose-bisphosphate aldolase, class II.
   
 
 0.900
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.899
SMC17668.1
Dihydrolipoamide dehydrogenase.
  
 0.856
gap
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.853
SMC17143.1
Fructose-bisphosphate aldolase, class II.
   
 
 0.770
SMC19926.1
Phosphoglycerate kinase.
  
 
 0.753
atpE
ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
  
 0.748
Your Current Organism:
Mycoplasma agassizii
NCBI taxonomy Id: 33922
Other names: ATCC 700616, CCUG 53180, M. agassizii, Mycoplasma agassizii Brown et al. 2001, strain PS6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.