Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yjjXNTPase; Pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)    
Predicted Functional Partners:
KOY81141.1
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.920
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
KOY81353.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.697
KOY81355.1
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.635
KOY81356.1
Peptidase M4; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.605
KOY81352.1
tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
     0.552
KOY83484.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.530
KOY81506.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.522
KOY84120.1
RocC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.467
KOY82864.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.449
Your Current Organism:
Lysinibacillus macroides
NCBI taxonomy Id: 33935
Other names: ATCC 12905, Bacillus macroides, DSM 54, L. macroides, LMG 18474, LMG:18474, Lineola longa
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