node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KZN94775.1 | KZN95904.1 | AZI98_17425 | AZI98_12615 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
KZN94775.1 | KZN95905.1 | AZI98_17425 | AZI98_12620 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.921 |
KZN94775.1 | KZN97329.1 | AZI98_17425 | AZI98_04075 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
KZN94775.1 | ribH | AZI98_17425 | AZI98_12605 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.911 |
KZN95716.1 | KZN95905.1 | AZI98_11595 | AZI98_12620 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.616 |
KZN95716.1 | guaB | AZI98_11595 | AZI98_12670 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.543 |
KZN95716.1 | ribBA | AZI98_11595 | AZI98_12610 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.635 |
KZN95716.1 | ribH | AZI98_11595 | AZI98_12605 | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.806 |
KZN95904.1 | KZN94775.1 | AZI98_12615 | AZI98_17425 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
KZN95904.1 | KZN95905.1 | AZI98_12615 | AZI98_12620 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
KZN95904.1 | KZN97329.1 | AZI98_12615 | AZI98_04075 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
KZN95904.1 | ribBA | AZI98_12615 | AZI98_12610 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
KZN95904.1 | ribH | AZI98_12615 | AZI98_12605 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.999 |
KZN95905.1 | KZN94775.1 | AZI98_12620 | AZI98_17425 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
KZN95905.1 | KZN95716.1 | AZI98_12620 | AZI98_11595 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.616 |
KZN95905.1 | KZN95904.1 | AZI98_12620 | AZI98_12615 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KZN95905.1 | KZN97329.1 | AZI98_12620 | AZI98_04075 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
KZN95905.1 | guaB | AZI98_12620 | AZI98_12670 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.579 |
KZN95905.1 | metK | AZI98_12620 | AZI98_01780 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.498 |
KZN95905.1 | nusB | AZI98_12620 | AZI98_09945 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.572 |