node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdd | guaA_2 | GTHT12_01993 | GTHT12_03347 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.503 |
cdd | pdp | GTHT12_01993 | GTHT12_01823 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Pyrimidine-nucleoside phosphorylase. | 0.998 |
cdd | punA | GTHT12_01993 | GTHT12_01824 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.947 |
cdd | yhcR | GTHT12_01993 | GTHT12_02496 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Endonuclease YhcR; Belongs to the 5'-nucleotidase family. | 0.917 |
cinA | yhcR | GTHT12_00721 | GTHT12_02496 | Putative competence-damage inducible protein; Belongs to the CinA family. | Endonuclease YhcR; Belongs to the 5'-nucleotidase family. | 0.922 |
guaA_2 | cdd | GTHT12_03347 | GTHT12_01993 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.503 |
guaA_2 | guaB | GTHT12_03347 | GTHT12_03055 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA_2 | pdp | GTHT12_03347 | GTHT12_01823 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Pyrimidine-nucleoside phosphorylase. | 0.562 |
guaA_2 | punA | GTHT12_03347 | GTHT12_01824 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.633 |
guaA_2 | purA | GTHT12_03347 | GTHT12_03019 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.919 |
guaA_2 | purB | GTHT12_03347 | GTHT12_03359 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.917 |
guaA_2 | purH | GTHT12_03347 | GTHT12_03367 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP cyclohydrolase. | 0.865 |
guaA_2 | yhcR | GTHT12_03347 | GTHT12_02496 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Endonuclease YhcR; Belongs to the 5'-nucleotidase family. | 0.936 |
guaB | guaA_2 | GTHT12_03055 | GTHT12_03347 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | pdp | GTHT12_03055 | GTHT12_01823 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pyrimidine-nucleoside phosphorylase. | 0.604 |
guaB | punA | GTHT12_03055 | GTHT12_01824 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.571 |
guaB | purA | GTHT12_03055 | GTHT12_03019 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.989 |
guaB | purB | GTHT12_03055 | GTHT12_03359 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.880 |
guaB | purH | GTHT12_03055 | GTHT12_03367 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | IMP cyclohydrolase. | 0.985 |
guaB | yhcR | GTHT12_03055 | GTHT12_02496 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Endonuclease YhcR; Belongs to the 5'-nucleotidase family. | 0.933 |