Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OJG21718.1YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (354 aa)    
Predicted Functional Partners:
OJG21717.1
Hypothetical protein.
  
 0.974
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
 
    0.918
hisC
Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.719
OJG20889.1
Threonine-phosphate decarboxylase.
  
  
 0.719
OJG21715.1
Hypothetical protein.
       0.717
DnaI
Primosomal protein DnaI.
       0.717
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.717
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.713
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.703
OJG21970.1
Peptidase T-like protein.
 
    0.688
Your Current Organism:
Enterococcus avium
NCBI taxonomy Id: 33945
Other names: ATCC 14025, CCUG 7983, CIP 103019, DSM 20679, E. avium, JCM 8722, LMG 10744, LMG:10744, NBRC 100477, NCDO 2369, NCIMB 702369, NCTC 9938, Streptococcus avium, strain Guthof E6844
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