mprF protein (Enterococcus avium) - STRING interaction network

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mprF

Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (326 aa)

Predicted Functional Partners:

pepT

0.765

OJG24396.1

0.726

OJG22918.1

0.719

OJG21718.1

0.717

OJG19750.1

0.686

OJG13956.1

0.648

OJG23013.1

0.646

OJG21715.1

0.636

OJG19111.1

0.602

PgsA

0.586

Your Current Organism:

Enterococcus avium

NCBI taxonomy Id: 33945
Other names: ATCC 14025, CCUG 7983, CIP 103019, DSM 20679, E. avium, JCM 8722, LMG 10744, LMG:10744, NBRC 100477, NCDO 2369, NCIMB 702369, NCTC 9938, Streptococcus avium, strain Guthof E6844

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OJG13956.1	OJG22918.1	RU95_GL004360	RU95_GL004095	Hypothetical protein.	Hypothetical protein.	0.565
OJG13956.1	OJG24396.1	RU95_GL004360	RU95_GL000082	Hypothetical protein.	Hypothetical protein.	0.556
OJG13956.1	mprF	RU95_GL004360	RU95_GL001079	Hypothetical protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.648
OJG19111.1	OJG22918.1	RU95_GL002479	RU95_GL004095	Hypothetical protein.	Hypothetical protein.	0.498
OJG19111.1	OJG23013.1	RU95_GL002479	RU95_GL003761	Hypothetical protein.	Hypothetical protein.	0.620
OJG19111.1	OJG24396.1	RU95_GL002479	RU95_GL000082	Hypothetical protein.	Hypothetical protein.	0.600
OJG19111.1	mprF	RU95_GL002479	RU95_GL001079	Hypothetical protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.602
OJG19750.1	mprF	RU95_GL002431	RU95_GL001079	Glycosyl transferase.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.686
OJG21715.1	OJG21718.1	RU95_GL001074	RU95_GL001077	Hypothetical protein.	YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	0.717
OJG21715.1	mprF	RU95_GL001074	RU95_GL001079	Hypothetical protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.636
OJG21715.1	pepT	RU95_GL001074	RU95_GL001078	Hypothetical protein.	Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.	0.702
OJG21718.1	OJG21715.1	RU95_GL001077	RU95_GL001074	YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	Hypothetical protein.	0.717
OJG21718.1	mprF	RU95_GL001077	RU95_GL001079	YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.717
OJG21718.1	pepT	RU95_GL001077	RU95_GL001078	YbgI/family dinuclear metal center protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.	0.918
OJG22918.1	OJG13956.1	RU95_GL004095	RU95_GL004360	Hypothetical protein.	Hypothetical protein.	0.565
OJG22918.1	OJG19111.1	RU95_GL004095	RU95_GL002479	Hypothetical protein.	Hypothetical protein.	0.498
OJG22918.1	OJG23013.1	RU95_GL004095	RU95_GL003761	Hypothetical protein.	Hypothetical protein.	0.591
OJG22918.1	OJG24396.1	RU95_GL004095	RU95_GL000082	Hypothetical protein.	Hypothetical protein.	0.727
OJG22918.1	mprF	RU95_GL004095	RU95_GL001079	Hypothetical protein.	Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.719
OJG23013.1	OJG19111.1	RU95_GL003761	RU95_GL002479	Hypothetical protein.	Hypothetical protein.	0.620

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