STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtfAAccessory Sec system translocase SecA2; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. (509 aa)    
Predicted Functional Partners:
gtfB
Accessory Sec system glycosylation chaperone GtfB; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
   
 0.978
BBP16_08080
Accessory Sec system protein Asp2; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.927
secY2
Accessory Sec system protein translocase subunit SecY2; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.872
AOG26751.1
Accessory Sec system protein Asp1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.817
AOG26769.1
Beta-1,6-galactofuranosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.779
AOG26755.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AOG26107.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.759
AOG26108.1
Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.756
AOG27122.1
Levansucrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.751
AOG27128.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.715
Your Current Organism:
Lactobacillus johnsonii
NCBI taxonomy Id: 33959
Other names: ATCC 33200, CCUG 30725, CIP 103620, DSM 10533, JCM 2012, L. johnsonii, VPI 7960
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.