Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (375 aa)    
Predicted Functional Partners:
menE
O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
 
  0.971
menB
Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
  
 0.724
KZL43354.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.655
KZL40053.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
    0.620
KZL42737.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.428
KZL40110.1
Macro domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.427
KZL39350.1
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
 
  
  0.424
KZL40138.1
Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
 
    0.402
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
Server load: low (22%) [HD]