Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KZL43217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NrdI family. (155 aa)    
Predicted Functional Partners:
KZL41580.1
Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
KZL41578.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
KZL41579.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.976
KZL39760.1
Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.807
KZL43216.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the flavin oxidoreductase frp family.
       0.762
KZL42654.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.683
KZL41717.1
IpaB/EvcA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.620
KZL43218.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.613
KZL42841.1
Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
     
 0.588
KZL42840.1
Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.587
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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