Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KZL42320.1Nickase; Derived by automated computational analysis using gene prediction method: Protein Homology. (661 aa)    
Predicted Functional Partners:
KZL42710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.622
KZL43287.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.620
KZL37158.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.610
KZL43256.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.595
addA
Hypothetical protein; ATP-dependent DNA helicase.
  
 
 0.564
KZL40016.1
Plasmid replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
KZL43168.1
Plasmid replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.522
KZL42316.1
Plasmid replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.496
KZL43279.1
Plasmid replication initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.477
KZL41034.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.469
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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