ldh protein (Lactobacillus collinoides) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ldh

Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (317 aa)

Predicted Functional Partners:

KZL41025.1

0.958

KZL42451.1

0.925

KZL37123.1

0.922

KZL42450.1

0.859

fumC

0.849

KZL42727.1

0.824

KZL38871.1

0.795

KZL39032.1

0.785

KZL42617.1

0.783

KZL37068.1

0.783

Your Current Organism:

Lactobacillus collinoides

NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KZL37068.1	KZL38871.1	TY91_13555	TY91_11185	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.569
KZL37068.1	KZL39032.1	TY91_13555	TY91_10835	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.609
KZL37068.1	KZL41025.1	TY91_13555	TY91_07170	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
KZL37068.1	KZL42727.1	TY91_13555	TY91_03430	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.573
KZL37068.1	ldh	TY91_13555	TY91_05550	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.	0.783
KZL37123.1	KZL38871.1	TY91_12850	TY91_11185	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.900
KZL37123.1	KZL39032.1	TY91_12850	TY91_10835	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
KZL37123.1	KZL41025.1	TY91_12850	TY91_07170	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.766
KZL37123.1	KZL42450.1	TY91_12850	TY91_04810	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
KZL37123.1	KZL42451.1	TY91_12850	TY91_04815	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.945
KZL37123.1	KZL42727.1	TY91_12850	TY91_03430	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.553
KZL37123.1	fumC	TY91_12850	TY91_11465	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.472
KZL37123.1	ldh	TY91_12850	TY91_05550	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.	0.922
KZL38871.1	KZL37068.1	TY91_11185	TY91_13555	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.569
KZL38871.1	KZL37123.1	TY91_11185	TY91_12850	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
KZL38871.1	KZL39032.1	TY91_11185	TY91_10835	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
KZL38871.1	KZL41025.1	TY91_11185	TY91_07170	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
KZL38871.1	KZL42451.1	TY91_11185	TY91_04815	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.930
KZL38871.1	KZL42617.1	TY91_11185	TY91_03950	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.569
KZL38871.1	KZL42727.1	TY91_11185	TY91_03430	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.886