Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KZL41186.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)    
Predicted Functional Partners:
KZL35792.1
Hypothetical protein; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.760
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.723
dltA
Hypothetical protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-bindin [...]
 
  
 0.712
KZL35794.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.664
KZL41091.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.618
dltC
Alanine-phosphoribitol ligase; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
   
 0.611
KZL43314.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
KZL39433.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.582
KZL41415.1
Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.551
KZL38969.1
Aspartate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.511
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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