Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KZL39359.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)    
Predicted Functional Partners:
KZL39360.1
Fructose permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.933
KZL39361.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.925
trpB
Phosphoribosylanthranilate isomerase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.861
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
  0.799
KZL39336.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.799
KZL40234.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
  0.751
dsdA
Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the serine/threonine dehydratase family. DsdA subfamily.
     
  0.739
KZL35849.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
KZL43339.1
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.716
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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