Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
KZL38927.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (473 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
  0.705
KZL40063.1
Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.660
KZL41115.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.651
KZL39421.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.
  
 
  0.574
KZL42740.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.511
KZL41407.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.511
KZL40128.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.511
KZL41037.1
30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.507
KZL41126.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.499
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.475
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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