STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZL35740.1Pyrimidine reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (343 aa)    
Predicted Functional Partners:
KZL35741.1
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 0.999
folE
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.947
KZL41161.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.925
KZL42971.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.919
KZL42716.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.914
KZL42618.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.914
KZL40117.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.914
KZL41568.1
Peptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.905
Your Current Organism:
Lactobacillus collinoides
NCBI taxonomy Id: 33960
Other names: ATCC 27612, CCUG 32259, CIP 103008, DSM 20515, L. collinoides, LMG 9194, LMG:9194
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