STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_0164PFAM: conserved hypothetical protein 743; KEGG: hdu:HD1892 hypothetical protein. (96 aa)    
Predicted Functional Partners:
Asuc_0644
PFAM: protein of unknown function DUF997; KEGG: msu:MS1787 hypothetical protein.
  
     0.772
lapA
Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.769
Asuc_0932
DNA polymerase III psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.768
Asuc_1497
PFAM: protein of unknown function DUF1043; KEGG: pmu:PM0688 hypothetical HI1628.
  
     0.761
mukF
Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.759
Asuc_2043
PFAM: protein of unknown function DUF331; KEGG: pmu:PM1129 hypothetical HI0235.
  
     0.754
mukB
Chromosome segregation and condensation protein MukB domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.752
mukE
Chromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.751
Asuc_0813
PFAM: lipopolysaccharide biosynthesis protein; KEGG: msu:MS0655 hypothetical protein.
  
     0.750
Asuc_0053
UspA domain protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
    0.742
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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