| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Asuc_0127 | Asuc_0914 | Asuc_0127 | Asuc_0914 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.985 |
| Asuc_0127 | Asuc_0975 | Asuc_0127 | Asuc_0975 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | 0.929 |
| Asuc_0127 | Asuc_0996 | Asuc_0127 | Asuc_0996 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: hit:NTHI2020 PTS system, glucose-specific IIA component. | 0.917 |
| Asuc_0127 | murQ | Asuc_0127 | Asuc_0257 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.904 |
| Asuc_0259 | anmK | Asuc_0259 | Asuc_0258 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msu:MS0394 ABC-type multidrug/protein/lipid transport system, ATPase component. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.605 |
| Asuc_0259 | murQ | Asuc_0259 | Asuc_0257 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msu:MS0394 ABC-type multidrug/protein/lipid transport system, ATPase component. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.609 |
| Asuc_0259 | recX | Asuc_0259 | Asuc_0260 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msu:MS0394 ABC-type multidrug/protein/lipid transport system, ATPase component. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.496 |
| Asuc_0914 | Asuc_0127 | Asuc_0914 | Asuc_0127 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | 0.985 |
| Asuc_0914 | Asuc_0975 | Asuc_0914 | Asuc_0975 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | 0.963 |
| Asuc_0914 | Asuc_0996 | Asuc_0914 | Asuc_0996 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: hit:NTHI2020 PTS system, glucose-specific IIA component. | 0.997 |
| Asuc_0914 | Asuc_1103 | Asuc_0914 | Asuc_1103 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: apl:APL_1756 N-acetylglucosamine-6-phosphate deacetylase. | 0.488 |
| Asuc_0914 | murQ | Asuc_0914 | Asuc_0257 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.519 |
| Asuc_0914 | nagK | Asuc_0914 | Asuc_1504 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.991 |
| Asuc_0914 | nagZ | Asuc_0914 | Asuc_0211 | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | Beta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.435 |
| Asuc_0975 | Asuc_0127 | Asuc_0975 | Asuc_0127 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: msu:MS1408 NagE protein. | 0.929 |
| Asuc_0975 | Asuc_0914 | Asuc_0975 | Asuc_0914 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: msu:MS0784 phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.963 |
| Asuc_0975 | Asuc_0996 | Asuc_0975 | Asuc_0996 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: hit:NTHI2020 PTS system, glucose-specific IIA component. | 0.922 |
| Asuc_0975 | Asuc_1103 | Asuc_0975 | Asuc_1103 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: apl:APL_1756 N-acetylglucosamine-6-phosphate deacetylase. | 0.670 |
| Asuc_0975 | murQ | Asuc_0975 | Asuc_0257 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.655 |
| Asuc_0975 | nagK | Asuc_0975 | Asuc_1504 | TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: bld:BLi04200 close homolog to BglP PTS enzyme IIBCA component; RBL02058. | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.993 |