node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Asuc_0713 | Asuc_0801 | Asuc_0713 | Asuc_0801 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.917 |
Asuc_0713 | Asuc_1135 | Asuc_0713 | Asuc_1135 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: msu:MS1520 cystathionine beta-lyases/cystathionine gamma-synthases. | 0.940 |
Asuc_0713 | Asuc_1191 | Asuc_0713 | Asuc_1191 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: msu:MS0941 MetE protein. | 0.906 |
Asuc_0713 | Asuc_1623 | Asuc_0713 | Asuc_1623 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: pmu:PM0738 cystathionine beta-lyase, putative. | 0.917 |
Asuc_0713 | Asuc_1846 | Asuc_0713 | Asuc_1846 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: msu:MS1627 cystathionine beta-lyases/cystathionine gamma-synthases. | 0.940 |
Asuc_0713 | Asuc_2108 | Asuc_0713 | Asuc_2108 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: msu:MS1770 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.823 |
Asuc_0713 | ilvA | Asuc_0713 | Asuc_0417 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.818 |
Asuc_0713 | luxS | Asuc_0713 | Asuc_0685 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.926 |
Asuc_0713 | thrB | Asuc_0713 | Asuc_0802 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.817 |
Asuc_0801 | Asuc_0713 | Asuc_0801 | Asuc_0713 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | 0.917 |
Asuc_0801 | Asuc_1135 | Asuc_0801 | Asuc_1135 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: msu:MS1520 cystathionine beta-lyases/cystathionine gamma-synthases. | 0.940 |
Asuc_0801 | Asuc_1191 | Asuc_0801 | Asuc_1191 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: msu:MS0941 MetE protein. | 0.917 |
Asuc_0801 | Asuc_1623 | Asuc_0801 | Asuc_1623 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: pmu:PM0738 cystathionine beta-lyase, putative. | 0.906 |
Asuc_0801 | Asuc_1846 | Asuc_0801 | Asuc_1846 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: msu:MS1627 cystathionine beta-lyases/cystathionine gamma-synthases. | 0.940 |
Asuc_0801 | Asuc_2108 | Asuc_0801 | Asuc_2108 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: msu:MS1770 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.417 |
Asuc_0801 | ilvA | Asuc_0801 | Asuc_0417 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.766 |
Asuc_0801 | luxS | Asuc_0801 | Asuc_0685 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.860 |
Asuc_0801 | thrB | Asuc_0801 | Asuc_0802 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
Asuc_1135 | Asuc_0713 | Asuc_1135 | Asuc_0713 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: msu:MS1520 cystathionine beta-lyases/cystathionine gamma-synthases. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: oih:OB1054 hypothetical protein. | 0.940 |
Asuc_1135 | Asuc_0801 | Asuc_1135 | Asuc_0801 | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: msu:MS1520 cystathionine beta-lyases/cystathionine gamma-synthases. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: msu:MS1703 aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.940 |