STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_0709TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: msu:MS1813 thiol-disulfide isomerase and thioredoxins. (175 aa)    
Predicted Functional Partners:
Asuc_0711
PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: msu:MS1811 TPR-repeat-containing proteins.
 
  
 0.960
Asuc_0710
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
  
 0.957
Asuc_0708
TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: msu:MS1815 cytochrome c biogenesis factor.
 
  
 0.942
Asuc_0848
TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: pmu:PM0010 cytochrome C-type biogenesis.
 
  
 0.896
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.859
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.842
Asuc_0850
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
  
 0.823
Asuc_0844
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.804
Asuc_0851
KEGG: msu:MS0609 NrfG protein.
 
  
 0.795
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.779
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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