STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_0921PFAM: protein of unknown function DUF496; KEGG: msu:MS1572 hypothetical protein; Belongs to the UPF0265 family. (114 aa)    
Predicted Functional Partners:
ftsL
Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.751
Asuc_1497
PFAM: protein of unknown function DUF1043; KEGG: pmu:PM0688 hypothetical HI1628.
  
     0.748
zapB
Protein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
    0.745
lapA
Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.740
Asuc_0309
PFAM: protein of unknown function DUF1040; KEGG: msu:MS2058 hypothetical protein.
  
     0.725
Asuc_0457
Mannitol repressor, MtlR; PFAM: Mannitol repressor; KEGG: msu:MS0409 mannitol operon repressor.
  
     0.720
mukE
Chromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.714
mukF
Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.711
Asuc_0164
PFAM: conserved hypothetical protein 743; KEGG: hdu:HD1892 hypothetical protein.
  
    0.709
Asuc_0361
PFAM: adenylate cyclase class-I; KEGG: pmu:PM1811 adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.
  
     0.694
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.