| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Asuc_0990 | Asuc_0991 | Asuc_0990 | Asuc_0991 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | 0.852 |
| Asuc_0990 | hflX | Asuc_0990 | Asuc_0986 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.640 |
| Asuc_0990 | hfq | Asuc_0990 | Asuc_0987 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.684 |
| Asuc_0990 | miaA | Asuc_0990 | Asuc_0988 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.882 |
| Asuc_0990 | mutL | Asuc_0990 | Asuc_0989 | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.883 |
| Asuc_0991 | Asuc_0990 | Asuc_0991 | Asuc_0990 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: msu:MS1515 N-acetylmuramoyl-L-alanine amidase. | 0.852 |
| Asuc_0991 | Asuc_1108 | Asuc_0991 | Asuc_1108 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | 0.953 |
| Asuc_0991 | Asuc_1702 | Asuc_0991 | Asuc_1702 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: msu:MS1037 putative translation factor (SUA5); Belongs to the SUA5 family. | 0.629 |
| Asuc_0991 | hflX | Asuc_0991 | Asuc_0986 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | Small GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.558 |
| Asuc_0991 | hfq | Asuc_0991 | Asuc_0987 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.598 |
| Asuc_0991 | mfd | Asuc_0991 | Asuc_0557 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.591 |
| Asuc_0991 | miaA | Asuc_0991 | Asuc_0988 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.873 |
| Asuc_0991 | mutL | Asuc_0991 | Asuc_0989 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.819 |
| Asuc_0991 | tsaC | Asuc_0991 | Asuc_0338 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | SUA5/yciO/yrdC domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.640 |
| Asuc_0991 | tsaD | Asuc_0991 | Asuc_2013 | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.853 |
| Asuc_1108 | Asuc_0991 | Asuc_1108 | Asuc_0991 | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase. | 0.953 |
| Asuc_1108 | Asuc_1702 | Asuc_1108 | Asuc_1702 | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: msu:MS1037 putative translation factor (SUA5); Belongs to the SUA5 family. | 0.646 |
| Asuc_1108 | miaA | Asuc_1108 | Asuc_0988 | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.467 |
| Asuc_1108 | tsaC | Asuc_1108 | Asuc_0338 | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | SUA5/yciO/yrdC domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.654 |
| Asuc_1108 | tsaD | Asuc_1108 | Asuc_2013 | PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein. | Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.964 |