Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Asuc_1027TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: msu:MS1739 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)    
Predicted Functional Partners:
pgk
PFAM: phosphoglycerate kinase; KEGG: msu:MS0245 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 0.999
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.997
Asuc_1575
PFAM: triosephosphate isomerase; phosphotransferase system PTS EIIB protein; KEGG: pmu:PM1640 triosephosphate isomerase.
 0.994
Asuc_0536
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.987
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: msu:MS1181 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.984
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 
 0.982
Asuc_1601
PFAM: triosephosphate isomerase; KEGG: pmu:PM1640 triosephosphate isomerase.
 0.978
Asuc_1171
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: msu:MS1197 pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.953
aptA
Transketolase domain protein; Involved in catabolism of D-apiose. Catalyzes the transfer of the glycolaldehyde group from apulose-4-phosphate to D-glyceraldehyde 3-phosphate, generating dihydroxyacetone phosphate and D-xylulose-5- phosphate.
  
 0.951
Asuc_0265
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.951
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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