STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_1118PFAM: protein of unknown function DUF1439; KEGG: msu:MS1449 hypothetical protein. (183 aa)    
Predicted Functional Partners:
Asuc_0999
KEGG: msu:MS0837 TorD protein.
  
     0.759
Asuc_0543
PFAM: YfbU family protein; KEGG: pmu:PM1500 hypothetical E.coli; Belongs to the UPF0304 family.
  
     0.715
Asuc_0250
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
  
     0.712
Asuc_1710
PFAM: protein of unknown function DUF412; KEGG: hso:HS_0804 hypothetical protein.
  
     0.702
Asuc_0778
PFAM: protein of unknown function DUF1414; KEGG: pmu:PM1884 hypothetical HI0840; Belongs to the UPF0352 family.
  
     0.700
Asuc_0538
PFAM: protein of unknown function DUF469; KEGG: msu:MS0319 hypothetical protein.
  
     0.695
Asuc_1259
PFAM: protein of unknown function DUF440; KEGG: msu:MS1016 hypothetical protein; Belongs to the UPF0263 family.
  
     0.686
Asuc_0961
KEGG: msu:MS0861 hypothetical protein.
  
     0.676
lapA
Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.666
matP
Protein of unknown function DUF1047; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.664
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.