STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (338 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.997
Asuc_0892
TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: msu:MS0775 biotin-(acetyl-CoA carboxylase) ligase.
  
 
 0.937
Asuc_0629
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pmu:PM1194 hypothetical HI0912.
  
  
 0.869
thiQ
ABC transporter, ATPase subunit, ThiQ subfamily; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
     
 0.815
Asuc_1130
TIGRFAM: thiamine ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: msu:MS1525 ABC-type thiamine transport system, permease components.
  
  
 0.801
Asuc_1129
TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; thiamine ABC transporter, periplasmic binding protein; KEGG: msu:MS1526 ABC-type iron/thiamine transport systems, periplasmic component.
       0.788
Asuc_1133
PFAM: protein of unknown function DUF488; KEGG: msu:MS1522 hypothetical protein.
       0.547
Asuc_0007
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: hin:HI0095 hypothetical protein.
  
  
 0.482
Asuc_1402
Putative permease; KEGG: hso:HS_0867 possible permease.
  
    0.478
Asuc_1705
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: msu:MS0731 GltD protein.
     
 0.446
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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