STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_1168PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: eca:ECA0078 2-hydroxyacid dehydrogenase. (324 aa)    
Predicted Functional Partners:
Asuc_1432
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: msu:MS1188 glycerate dehydrogenase.
  
  
 
0.921
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
  0.914
Asuc_1808
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
   
 0.910
Asuc_1857
PFAM: glycerate kinase; KEGG: msu:MS0693 glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.908
Asuc_1854
PFAM: Arylesterase; SMP-30/Gluconolaconase/LRE domain protein; KEGG: msu:MS0684 gluconolactonase.
  
 
 0.907
Asuc_0152
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: msu:MS0546 2-keto-3-deoxy-6-phosphogluconate aldolase.
    
  0.902
Asuc_1471
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: msu:MS0566 2-keto-3-deoxy-6-phosphogluconate aldolase.
    
  0.902
garR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
    
  0.902
Asuc_1154
TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: msu:MS0957 gluconate kinase.
     
  0.900
Asuc_1167
PFAM: PfkB domain protein; KEGG: bpm:BURPS1710b_2288 2-dehydro-3-deoxygluconokinase.
 
    0.841
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.