STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_1195TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; KEGG: hdu:HD1242 citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (297 aa)    
Predicted Functional Partners:
citD
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
 
 
 0.997
Asuc_1196
TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit; KEGG: hin:HI0022 citrate lyase alpha chain.
 
 
 0.997
citG
Holo-ACP synthase, Triphosphoribosyl-dephospho-CoA synthase; PFAM: triphosphoribosyl-dephospho-CoA protein; Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; KEGG: hit:NTHI0028 CitXG.
 
  
 0.997
Asuc_0305
Citrate lyase ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
  
 0.959
Asuc_0121
PFAM: class II aldolase/adducin family protein; KEGG: msu:MS1979 hypothetical protein.
   
    0.695
Asuc_0234
TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; KEGG: msu:MS0046 ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.
   
    0.695
Asuc_1197
Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
       0.547
Asuc_0302
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: msu:MS0039 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, alpha subunit.
  
  
 0.532
purR
Periplasmic binding protein/LacI transcriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
  
    0.513
Asuc_1303
PFAM: Citrate transporter; KEGG: bha:BH0745 magnesium citrate secondary transporter.
 
     0.420
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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