STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhEFormate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (299 aa)    
Predicted Functional Partners:
Asuc_1262
TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: msu:MS1028 cytochrome b subunit of formate dehydrogenase.
 
  
 0.936
Asuc_1264
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: msu:MS0891 anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 
 0.922
Asuc_1265
Formate dehydrogenase; PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: msu:MS0892 anaerobic dehydrogenases, typically selenocysteine-containing.
 
 
 
 0.909
Asuc_1263
Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
  
 0.892
Asuc_0442
TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: msu:MS2339 selenocysteine-specific translation elongation factor.
 
   
 0.775
selA
L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
   
 0.675
Asuc_1560
Transcriptional regulator, ModE family; TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein LysR; TOBE domain protein; Transport-associated OB domain protein; KEGG: pmu:PM0746 molybdenum transport protein.
 
   
 0.631
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.565
Asuc_1450
PFAM: protein of unknown function DUF945; KEGG: msu:MS0897 hypothetical protein.
  
     0.519
Asuc_1259
PFAM: protein of unknown function DUF440; KEGG: msu:MS1016 hypothetical protein; Belongs to the UPF0263 family.
       0.510
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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