STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Asuc_1424PFAM: major facilitator superfamily MFS_1; KEGG: msu:MS1178 permeases of the major facilitator superfamily. (390 aa)    
Predicted Functional Partners:
mukF
Chromosome segregation and condensation protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.660
mukE
Chromosome segregation and condensation protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.650
Asuc_0813
PFAM: lipopolysaccharide biosynthesis protein; KEGG: msu:MS0655 hypothetical protein.
  
     0.609
Asuc_0164
PFAM: conserved hypothetical protein 743; KEGG: hdu:HD1892 hypothetical protein.
  
     0.596
mukB
Chromosome segregation and condensation protein MukB domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.566
Asuc_1423
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.556
Asuc_0935
KEGG: hso:HS_0606 hypothetical protein.
  
   
 0.554
Asuc_0053
UspA domain protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
     0.535
Asuc_0921
PFAM: protein of unknown function DUF496; KEGG: msu:MS1572 hypothetical protein; Belongs to the UPF0265 family.
  
     0.501
Asuc_0361
PFAM: adenylate cyclase class-I; KEGG: pmu:PM1811 adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.
  
     0.473
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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