| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Asuc_0114 | Asuc_1965 | Asuc_0114 | Asuc_1965 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.549 |
| Asuc_0114 | uppS | Asuc_0114 | Asuc_1967 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.428 |
| Asuc_0250 | Asuc_0251 | Asuc_0250 | Asuc_0251 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | PFAM: MucB/RseB family protein; KEGG: pmu:PM1787 sigma-E factor regulatory protein. | 0.997 |
| Asuc_0250 | Asuc_1369 | Asuc_0250 | Asuc_1369 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pmu:PM0748 protease DegS precursor. | 0.887 |
| Asuc_0250 | Asuc_1963 | Asuc_0250 | Asuc_1963 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | 0.484 |
| Asuc_0250 | Asuc_1965 | Asuc_0250 | Asuc_1965 | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.501 |
| Asuc_0251 | Asuc_0250 | Asuc_0251 | Asuc_0250 | PFAM: MucB/RseB family protein; KEGG: pmu:PM1787 sigma-E factor regulatory protein. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.997 |
| Asuc_0251 | Asuc_1965 | Asuc_0251 | Asuc_1965 | PFAM: MucB/RseB family protein; KEGG: pmu:PM1787 sigma-E factor regulatory protein. | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.501 |
| Asuc_1084 | Asuc_1965 | Asuc_1084 | Asuc_1965 | TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; KEGG: msu:MS0821 periplasmic protease; Belongs to the peptidase S41A family. | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.511 |
| Asuc_1369 | Asuc_0250 | Asuc_1369 | Asuc_0250 | TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pmu:PM0748 protease DegS precursor. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.887 |
| Asuc_1369 | Asuc_1965 | Asuc_1369 | Asuc_1965 | TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pmu:PM0748 protease DegS precursor. | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.521 |
| Asuc_1963 | Asuc_0250 | Asuc_1963 | Asuc_0250 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.484 |
| Asuc_1963 | Asuc_1965 | Asuc_1963 | Asuc_1965 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | 0.686 |
| Asuc_1963 | Asuc_1966 | Asuc_1963 | Asuc_1966 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | PFAM: phosphatidate cytidylyltransferase; KEGG: msu:MS1926 CDP-diglyceride synthetase; Belongs to the CDS family. | 0.480 |
| Asuc_1963 | bamA | Asuc_1963 | Asuc_1964 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.867 |
| Asuc_1963 | lpxD | Asuc_1963 | Asuc_1962 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.908 |
| Asuc_1963 | uppS | Asuc_1963 | Asuc_1967 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: msu:MS1923 outer membrane protein; Belongs to the skp family. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.473 |
| Asuc_1965 | Asuc_0114 | Asuc_1965 | Asuc_0114 | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.549 |
| Asuc_1965 | Asuc_0250 | Asuc_1965 | Asuc_0250 | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.501 |
| Asuc_1965 | Asuc_0251 | Asuc_1965 | Asuc_0251 | TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: msu:MS1925 predicted membrane-associated Zn-dependent proteases 1. | PFAM: MucB/RseB family protein; KEGG: pmu:PM1787 sigma-E factor regulatory protein. | 0.501 |
