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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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tsaDPutative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (345 aa)    
Predicted Functional Partners:
Asuc_1108
PFAM: peptidase M22 glycoprotease; KEGG: msu:MS1360 hypothetical protein.
  
 
 0.924
Asuc_0991
PFAM: protein of unknown function UPF0079; KEGG: msu:MS1514 predicted ATPase or kinase.
 
 
 0.833
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: msu:MS1090 phenylalanyl-tRNA synthetase beta subunit.
 
   
 0.696
tsaC
SUA5/yciO/yrdC domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
 
 0.689
Asuc_0383
Conserved hypothetical protein; KEGG: pmu:PM0673 hypothetical HI1326.
  
 0.655
kdkA
Mn2+-dependent serine/threonine protein kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
  
 0.655
Asuc_1702
TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: msu:MS1037 putative translation factor (SUA5); Belongs to the SUA5 family.
  
 0.644
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.636
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
 
 
 0.635
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.593
Your Current Organism:
Actinobacillus succinogenes
NCBI taxonomy Id: 339671
Other names: A. succinogenes 130Z, Actinobacillus succinogenes 130Z, Actinobacillus succinogenes str. 130Z, Actinobacillus succinogenes strain 130Z
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