STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)    
Predicted Functional Partners:
udk
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.961
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.950
pyrR
Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.923
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.817
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.657
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.656
pheS
phenylalanine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
     
 0.617
OQJ73734.1
Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.606
tdk
MFS transporter; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.581
Your Current Organism:
Leuconostoc pseudomesenteroides
NCBI taxonomy Id: 33968
Other names: ATCC 12291, CCUG 30063, CIP 103316, DSM 20193, JCM 9696, KCTC 3652, L. pseudomesenteroides, LMG 11482, LMG:11482, NCCB 83005, NCDO 768, NCIMB 8699, strain 39, strain Moss 39
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