STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (341 aa)    
Predicted Functional Partners:
OQJ72224.1
1,2-diacylglycerol 3-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.892
OQJ72225.1
Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.859
OQJ72227.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.841
OQJ72228.1
Glycerol phosphate lipoteichoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.743
OQJ72927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.715
OQJ72223.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.584
OQJ72222.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.564
OQJ73310.1
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.522
OQJ71924.1
Nitrate ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.480
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.428
Your Current Organism:
Leuconostoc pseudomesenteroides
NCBI taxonomy Id: 33968
Other names: ATCC 12291, CCUG 30063, CIP 103316, DSM 20193, JCM 9696, KCTC 3652, L. pseudomesenteroides, LMG 11482, LMG:11482, NCCB 83005, NCDO 768, NCIMB 8699, strain 39, strain Moss 39
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.