STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_00016ATG11 domain-containing protein. (1305 aa)    
Predicted Functional Partners:
HCAG_07089
Protein kinase domain-containing protein.
    
 0.995
HCAG_05812
Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.
    
 0.987
HCAG_05295
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
 0.982
HCAG_01882
Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.964
HCAG_08387
Uncharacterized protein.
    
 0.958
HCAG_08094
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.920
HCAG_04969
Serine/threonine-protein phosphatase.
    
  0.913
HCAG_08430
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.913
HCAG_00848
Arp2/3 complex subunit; Belongs to the actin family.
    
  0.911
HCAG_05366
WD-repeat protein mip1.
    
  0.908
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.