HCAG_00065 protein (Histoplasma capsulatum NAm1)

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HCAG_00065

Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (328 aa)

Predicted Functional Partners:

HCAG_03853

0.636

HCAG_01221

0.513

HCAG_02294

0.483

HCAG_06125

0.447

HCAG_05744

0.444

HCAG_07928

0.442

HCAG_04989

0.439

HCAG_05452

0.436

HCAG_05453

0.436

HCAG_02566

0.424

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_00065	HCAG_01221	A6QRQ9	A6QV14	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.513
HCAG_00065	HCAG_02294	A6QRQ9	A6QY37	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.483
HCAG_00065	HCAG_02566	A6QRQ9	A6QYV9	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.424
HCAG_00065	HCAG_03853	A6QRQ9	A6R2J5	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	0.636
HCAG_00065	HCAG_04989	A6QRQ9	A6R5T1	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.439
HCAG_00065	HCAG_05452	A6QRQ9	A6R744	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.436
HCAG_00065	HCAG_05453	A6QRQ9	A6R745	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.436
HCAG_00065	HCAG_05744	A6QRQ9	A6R9V6	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.444
HCAG_00065	HCAG_06125	A6QRQ9	A6RAY7	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	Uncharacterized protein.	0.447
HCAG_00065	HCAG_07928	A6QRQ9	A6RE63	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.442
HCAG_01221	HCAG_00065	A6QV14	A6QRQ9	Uncharacterized protein.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.513
HCAG_02294	HCAG_00065	A6QY37	A6QRQ9	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.483
HCAG_02294	HCAG_02566	A6QY37	A6QYV9	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.608
HCAG_02294	HCAG_03853	A6QY37	A6R2J5	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	0.960
HCAG_02294	HCAG_05744	A6QY37	A6R9V6	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Uncharacterized protein.	0.999
HCAG_02294	HCAG_07928	A6QY37	A6RE63	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.609
HCAG_02566	HCAG_00065	A6QYV9	A6QRQ9	Uncharacterized protein.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.424
HCAG_02566	HCAG_02294	A6QYV9	A6QY37	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.608
HCAG_02566	HCAG_05744	A6QYV9	A6R9V6	Uncharacterized protein.	Uncharacterized protein.	0.588
HCAG_02566	HCAG_07928	A6QYV9	A6RE63	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.664