STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_00078Uncharacterized protein; Belongs to the cyclin family. (1153 aa)    
Predicted Functional Partners:
HCAG_03109
Protein kinase domain-containing protein.
    
 0.994
HCAG_00490
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.948
HCAG_02364
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.923
HCAG_06230
Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.881
HCAG_04046
Serine/threonine-protein kinase crk1; Belongs to the protein kinase superfamily.
     
 0.858
HCAG_02903
CYCLIN domain-containing protein; Belongs to the cyclin family.
     
 0.856
HCAG_08376
Spt4 domain-containing protein.
    
 0.828
HCAG_00038
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 
 0.809
HCAG_01109
Serine/threonine-protein kinase prk1.
    
 0.802
HCAG_01366
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
0.771
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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