STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_01469tRNA ligase. (815 aa)    
Predicted Functional Partners:
HCAG_06460
Yae1_N domain-containing protein.
   
  
 0.619
HCAG_00904
tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]
      
 0.608
HCAG_03304
Uncharacterized protein.
      
 0.608
HCAG_04676
Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.
      
 0.608
HCAG_04922
tRNA_int_end_N2 domain-containing protein.
      
 0.607
HCAG_07628
BZIP domain-containing protein.
      
 0.522
TIF1
ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
      
 0.448
HCAG_00215
Phenylalanyl-tRNA synthetase.
      
 0.447
HCAG_05805
Heat shock 70 kDa protein C; Belongs to the heat shock protein 70 family.
      
 0.445
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
Server load: low (22%) [HD]