STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_01575Saccharopine dehydrogenase. (457 aa)    
Predicted Functional Partners:
HCAG_01145
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.
  
 
 0.981
HCAG_09107
L-aminoadipate-semialdehyde dehydrogenase large subunit.
  
 
 0.938
HCAG_04999
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
    
 0.916
HCAG_07785
Homoisocitrate dehydrogenase, mitochondrial.
   
  
 0.818
HCAG_06854
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
  
 0.698
HCAG_06269
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.668
HCAG_05953
Tryptophan synthase.
  
  
 0.626
HCAG_07805
Argininosuccinate lyase.
 
 
  
 0.578
HCAG_06098
Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
  
 0.544
HCAG_03111
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  
 0.510
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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