STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_01596Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)    
Predicted Functional Partners:
HCAG_08805
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.984
HCAG_08647
Uncharacterized protein.
  
 0.945
HCAG_06059
Methylmalonate-semialdehyde dehydrogenase, mitochondrial.
   
 0.926
HCAG_03803
Hydroxymethylglutaryl-CoA lyase, mitochondrial.
  
 
 0.924
HCAG_05738
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.924
HCAG_08621
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
0.911
HCAG_08510
Uncharacterized protein.
   
 0.909
HCAG_05311
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
 
 
 0.898
HCAG_01606
Acetyl-coenzyme A synthetase.
  
 
 0.886
HCAG_07419
Uncharacterized protein.
  
 
 0.886
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.