HCAG_01670 protein (Histoplasma capsulatum NAm1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HCAG_01670

S5A_REDUCTASE domain-containing protein. (197 aa)

Predicted Functional Partners:

HCAG_07127

0.891

HCAG_08337

0.836

HCAG_01309

0.785

HCAG_07688

0.785

HCAG_05332

0.783

HCAG_05786

0.783

HCAG_07510

0.783

HCAG_01671

0.636

HCAG_08974

0.426

HCAG_03256

0.411

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01309	HCAG_01670	A6QVA2	A6QWB3	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	S5A_REDUCTASE domain-containing protein.	0.785
HCAG_01309	HCAG_07127	A6QVA2	A6RBW9	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.964
HCAG_01309	HCAG_08337	A6QVA2	A6RFC1	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	Uncharacterized protein.	0.573
HCAG_01670	HCAG_01309	A6QWB3	A6QVA2	S5A_REDUCTASE domain-containing protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.785
HCAG_01670	HCAG_01671	A6QWB3	A6QWB4	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.636
HCAG_01670	HCAG_03256	A6QWB3	A6R0U9	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.411
HCAG_01670	HCAG_05332	A6QWB3	A6R6S4	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_05786	A6QWB3	A6R9Z8	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_07127	A6QWB3	A6RBW9	S5A_REDUCTASE domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.891
HCAG_01670	HCAG_07510	A6QWB3	A6RD02	S5A_REDUCTASE domain-containing protein.	BZIP domain-containing protein.	0.783
HCAG_01670	HCAG_07688	A6QWB3	A6RDI0	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.785
HCAG_01670	HCAG_08337	A6QWB3	A6RFC1	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.836
HCAG_01670	HCAG_08974	A6QWB3	A6RH57	S5A_REDUCTASE domain-containing protein.	Nonspecific lipid-transfer protein, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.426
HCAG_01671	HCAG_01670	A6QWB4	A6QWB3	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.636
HCAG_03256	HCAG_01670	A6R0U9	A6QWB3	Uncharacterized protein.	S5A_REDUCTASE domain-containing protein.	0.411
HCAG_05332	HCAG_01670	A6R6S4	A6QWB3	BZIP domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.783
HCAG_05332	HCAG_07127	A6R6S4	A6RBW9	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.589
HCAG_05332	HCAG_08337	A6R6S4	A6RFC1	BZIP domain-containing protein.	Uncharacterized protein.	0.573
HCAG_05786	HCAG_01670	A6R9Z8	A6QWB3	BZIP domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.783
HCAG_05786	HCAG_07127	A6R9Z8	A6RBW9	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.589