STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_02571Pyruvate decarboxylase. (571 aa)    
Predicted Functional Partners:
HCAG_07206
S-(Hydroxymethyl)glutathione dehydrogenase.
   
 
 0.956
HCAG_08561
Alcohol dehydrogenase I.
 
 
 
 0.947
HCAG_07781
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.942
HCAG_06397
Alcohol dehydrogenase II.
 
 
 
 0.940
HCAG_08367
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.928
HCAG_06205
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.924
HCAG_08825
Dihydrolipoyl dehydrogenase.
   
 
 0.924
HCAG_07619
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.918
HCAG_01360
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.911
HCAG_03972
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.908
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
Server load: low (28%) [HD]