STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_04663Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (750 aa)    
Predicted Functional Partners:
HCAG_06635
ERCC4 domain-containing protein.
    
 0.779
HCAG_03230
ERCC4 domain-containing protein.
    
 0.778
HCAG_00537
Uncharacterized protein.
   
 
 0.716
HCAG_00984
Asparaginyl-tRNA synthetase.
   
 
 0.685
HCAG_08282
DRMBL domain-containing protein.
    
 0.618
HCAG_04753
Uncharacterized protein.
     
 0.617
HCAG_06272
DNA_mis_repair domain-containing protein.
   
 
 0.605
HCAG_05977
Uncharacterized protein.
   
 
 0.595
HCAG_05746
HECT domain-containing protein.
      
 0.531
HCAG_07918
UmuC domain-containing protein.
   
  
 0.527
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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