STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPL4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (642 aa)    
Predicted Functional Partners:
HCAG_02080
Uncharacterized protein.
   
 0.999
HCAG_02452
Cell division cycle protein 48; Belongs to the AAA ATPase family.
   
 0.999
HCAG_06392
UBX domain-containing protein.
    
 0.997
HCAG_06091
Polyubiquitin.
   
 0.984
HCAG_00738
Uncharacterized protein.
   
 
 0.979
HCAG_05170
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 
 0.973
HCAG_03521
OTU domain-containing protein.
    
 
 0.970
HCAG_05567
U-box domain-containing protein.
    
 
 0.970
HCAG_03048
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 
 0.965
HCAG_06566
Ubiquitin/79aa fusion protein.
   
 0.962
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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