STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_05730Uncharacterized protein. (307 aa)    
Predicted Functional Partners:
HCAG_01742
Adenylyl-sulfate kinase.
  
 
 0.987
MET3
Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.
    
 0.963
HCAG_01216
PAPS_reduct domain-containing protein.
  
 
 0.945
HCAG_02773
ATP_transf domain-containing protein.
     
  0.900
LAP1
Leucine aminopeptidase 1; Extracellular aminopeptidase that allows assimilation of proteinaceous substrates; Belongs to the peptidase M28 family. M28E subfamily.
 
      0.835
HCAG_05953
Tryptophan synthase.
  
  
 0.701
HCAG_00748
Anthranilate synthase component II.
   
  
 0.654
HCAG_08809
Exonuclease domain-containing protein.
      
 0.609
HCAG_02035
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
   
  
 0.607
HCAG_07645
DAGKc domain-containing protein.
      
 0.558
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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