STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_05920E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2174 aa)    
Predicted Functional Partners:
HCAG_05746
HECT domain-containing protein.
   
 0.997
HCAG_08618
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.950
HCAG_06091
Polyubiquitin.
   
 0.805
HCAG_06566
Ubiquitin/79aa fusion protein.
   
 0.737
HCAG_07333
Uncharacterized protein.
   
 
 0.671
HCAG_05935
Uncharacterized protein.
   
 
 0.639
HCAG_06716
Uncharacterized protein.
   
 0.601
HCAG_07229
Uncharacterized protein.
   
 0.586
HCAG_01668
DNA binding protein URE-B1.
   
 
 0.577
HCAG_02770
Uncharacterized protein.
    
 
 0.562
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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