STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_07445Thioredoxin domain-containing protein. (346 aa)    
Predicted Functional Partners:
HCAG_00748
Anthranilate synthase component II.
  
 
  0.953
HCAG_05953
Tryptophan synthase.
  
 
  0.943
HCAG_07459
NADH-ubiquinone oxidoreductase 21.3 kDa subunit.
 
 
  
 0.698
HCAG_06210
Thiol-specific antioxidant.
  
 
 0.671
HCAG_07019
Thioredoxin reductase.
  
  
 0.653
HCAG_04544
Peptide methionine sulfoxide reductase msrA.
  
  
 0.649
HCAG_04986
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
 0.633
HCAG_04127
Arabinan endo-1,5-alpha-L-arabinosidase; Belongs to the glycosyl hydrolase 43 family.
    
  0.615
HCAG_05000
Transketolase 1.
    
  0.615
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
     
 0.497
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.