HCAG_08114 protein (Histoplasma capsulatum NAm1)

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Score

HCAG_08114

3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)

Predicted Functional Partners:

HCAG_08805

0.984

HCAG_08647

0.945

HCAG_06059

0.926

HCAG_03803

0.924

HCAG_05738

0.924

HCAG_08621

0.911

HCAG_08510

0.909

HCAG_05311

0.899

HCAG_01606

0.886

HCAG_07419

0.886

Your Current Organism:

Histoplasma capsulatum NAm1

NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCAG_01606	HCAG_06059	A6QW49	A6RAS1	Acetyl-coenzyme A synthetase.	Methylmalonate-semialdehyde dehydrogenase, mitochondrial.	0.915
HCAG_01606	HCAG_07419	A6QW49	A6RCR1	Acetyl-coenzyme A synthetase.	Uncharacterized protein.	0.910
HCAG_01606	HCAG_08114	A6QW49	A6REP9	Acetyl-coenzyme A synthetase.	3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family.	0.886
HCAG_01606	HCAG_08621	A6QW49	A6RG55	Acetyl-coenzyme A synthetase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.946
HCAG_03803	HCAG_05311	A6R2E5	A6R6Q3	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.951
HCAG_03803	HCAG_05738	A6R2E5	A6R9V0	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	Pyruvate carboxyltransferase domain-containing protein.	0.903
HCAG_03803	HCAG_08114	A6R2E5	A6REP9	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
HCAG_03803	HCAG_08621	A6R2E5	A6RG55	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
HCAG_03803	HCAG_08805	A6R2E5	A6RGN8	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.965
HCAG_05311	HCAG_03803	A6R6Q3	A6R2E5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	0.951
HCAG_05311	HCAG_05738	A6R6Q3	A6R9V0	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Pyruvate carboxyltransferase domain-containing protein.	0.951
HCAG_05311	HCAG_08114	A6R6Q3	A6REP9	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family.	0.899
HCAG_05311	HCAG_08621	A6R6Q3	A6RG55	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.952
HCAG_05311	HCAG_08805	A6R6Q3	A6RGN8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.944
HCAG_05738	HCAG_03803	A6R9V0	A6R2E5	Pyruvate carboxyltransferase domain-containing protein.	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	0.903
HCAG_05738	HCAG_05311	A6R9V0	A6R6Q3	Pyruvate carboxyltransferase domain-containing protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.951
HCAG_05738	HCAG_08114	A6R9V0	A6REP9	Pyruvate carboxyltransferase domain-containing protein.	3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
HCAG_05738	HCAG_08621	A6R9V0	A6RG55	Pyruvate carboxyltransferase domain-containing protein.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
HCAG_05738	HCAG_08805	A6R9V0	A6RGN8	Pyruvate carboxyltransferase domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.965
HCAG_06059	HCAG_01606	A6RAS1	A6QW49	Methylmalonate-semialdehyde dehydrogenase, mitochondrial.	Acetyl-coenzyme A synthetase.	0.915