STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCAG_08810Uncharacterized protein. (684 aa)    
Predicted Functional Partners:
HCAG_01970
Uncharacterized protein.
   
 0.956
HCAG_03024
Uncharacterized protein.
   
 0.953
HCAG_07839
CDC73_C domain-containing protein.
   
 0.949
HCAG_04635
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.915
HCAG_08845
Plus3 domain-containing protein.
   
 0.911
HCAG_02041
Uncharacterized protein.
    
 0.909
HCAG_08809
Exonuclease domain-containing protein.
 
      0.841
HCAG_03525
Histone H2B; Belongs to the histone H2B family.
    
 0.829
HCAG_05932
RPOLD domain-containing protein.
   
 0.821
HCAG_08376
Spt4 domain-containing protein.
    
 0.792
Your Current Organism:
Histoplasma capsulatum NAm1
NCBI taxonomy Id: 339724
Other names: Ajellomyces capsulatus NAm1, H. capsulatum NAm1
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