STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (197 aa)    
Predicted Functional Partners:
pyrG
PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.931
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.929
Msp_0254
Anaerobic ribonucleotide-triphosphate reductase.
 
  
 0.921
Msp_0604
Predicted deoxycytidine triphosphate deaminase; COG0717, pfam0692.
  
  
  0.918
glyS
GlyS; glycyl-tRNA synthetase; COG0423, pfam00587, cd00774.
       0.904
Msp_1047
Predicted rRNA methylase; COG0565, pfam00588.
       0.881
Msp_1050
Predicted metal-dependent hydrolase; COG1099, pfam01026, cd01310.
       0.771
Msp_1051
Hypothetical membrane-spanning protein.
       0.600
tfrB
TfrB; Thiol:fumarate reductase, subunit B; COG0247, pfam02754.
  
    0.567
Msp_1116
Predicted dTDP-4-dehydrorhamnose reductase; COG1091, pfam04321.
   
    0.563
Your Current Organism:
Methanosphaera stadtmanae
NCBI taxonomy Id: 339860
Other names: M. stadtmanae DSM 3091, Methanosphaera stadtmanae ATCC 43021, Methanosphaera stadtmanae DSM 3091, Methanosphaera stadtmanae MCB-3, Methanosphaera stadtmanae str. DSM 3091, Methanosphaera stadtmanae strain DSM 3091
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